WHO, UNAIDS, and Jhpiego developed the Manual for Male Circumcision Under Local Anesthesia in 2008 to serve as the international technical resource for HIV prevention programs introducing medical male circumcision services. To date, the manual has been adopted or adapted for use in 14 African countries. To complement this, COSECSA, CDC, and PSI developed the Adverse Event (AE) Action Guide, standardizing the diagnosis and management of AEs. Both documents have served the needs of health ministries, policy makers, trainers, and health care workers in reaching over 10 million boys and men with safe circumcision for HIV prevention by 2015. Since initial editions of both manuals, extensive experience and standard practice have advanced. This year, WHO and Jhpiego will launch the Manual for Male Circumcision under Local Anaesthesia: For Providers Serving Adolescents and Adults, 2nd edition and COSECSA, CDC, and PSI will launch the 2nd edition of the AE Action Guide, both highlighting key updates of relevance to program planners and service providers.