Changes in Sexual Risk Behavior Before and After HIV Seroconversion in Southern African Women Enrolled in a HIV Prevention Trial
Venkatesh, K.K., de Bruyn, G., Mayer, K.H., et al. Journal of Acquired Immune Deficiency Syndromes (August 2011), 57(5): 435–441.
This study looked at women's sexual behavior before and after seroconversion. The subjects comprised 327 women who became HIV-positive while participating in a randomized controlled trial of lubricant gel and diaphragm use for HIV prevention in southern Africa. Every three months, the women gave information about sexual practices using computer-assisted self-interviews. Findings showed that they reduced their sexual risk behaviors, such as unprotected sex, anal sex, multiple sexual partners, and inconsistent condom use after seroconversion. However, the reduction in frequency of risk behaviors was modest: typically a 10 percent change. These findings, the authors said, suggested a need for more secondary prevention. The study design had several strengths, such as frequent interviewing, which reduces the risk of recall bias, and data collection both before and after seroconversion.