Combination Prevention Knowledge Base

December 2016 - Reports, Guidelines, and Tools

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AIDSFree (2016).

The HIV Prevention Knowledge Base (PKB) is a collection of research and tools to help you find what works in prevention. Each PKB topic includes a short introduction that describes the approach, synthesizes the core elements of the intervention, and reviews the current state of practice. The PKB includes databases for combination, biomedical, behavioral, and structural prevention; entries within each database summarize evidence, tools, and resources for 29 approaches for prevention. A sample of the approaches under each category includes:

  • Combination Prevention (5 topics): This category includes approaches for various high-risk groups such as men who have sex with men, people who inject drugs, and serodiscordant couples; and describes approaches for promoting positive health while reducing risks of transmitting the virus to others.
  • Biomedical Prevention (12 topics): This category covers a wide range of procedures (such as ensuring the safety of blood supplies or injections), medical protocols (such as male circumcision and prevention of mother-to-child transmission), and medicines (such as antiretrovirals and microbicides) that prevent HIV or mitigate its effect.
  • Behavioral Prevention (9 topics): This category covers approaches for reducing high-risk behavior, including consistent condom use, peer-based interventions, partner reduction, and alcohol-related risks, among others.
  • Structural Prevention (3 topics): This category comprises an overview and sections on policy-focused and work-based interventions.

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