Crepaz, N., Tungol-Ashmon, M.V., Vosburgh, H.W., et al. AIDS Care (November 2015), 27(11):1361-1366, doi: 10.1080/09540121.2015.1112353.
This systematic review and meta-analysis examined studies that compared the effects of couple-based versus individual-level interventions, and estimated the strength of couple-based intervention effects on HIV protective behaviors. A total of 15 couple-based interventions conducted between January 1988 and December 2014, with a total of 21,882 participants, met the inclusion criteria. The authors found that the results of random-effects models showed statistically significant intervention effects for protected sex, HIV testing, and nevirapine uptake. They concluded that couple-based interventions were more effective in promoting these protective behaviors when directly compared to interventions delivered to individuals. They added that couples HIV counseling and testing allowed both members of a couple to learn their HIV status and make informed choices about antiretroviral prophylaxis during pregnancy (for heterosexual couples) and antiretroviral therapy.