Optimal Timing of Viral Load Monitoring During Pregnancy to Predict Viraemia at Delivery in HIV-Infected Women Initiating ART in South Africa: A Simulation Study

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Lesosky M. et al. JIAS (2017), 20(S7): e25000. doi:10.1002/jia2.25000.

While HIV viral load (VL) monitoring is a central tool to evaluate ART effectiveness and transmission risk, there has been little research into VL monitoring in pregnant women. This study explored when and how frequently VL should be monitored in women initiating ART during pregnancy to predict VL at the time of delivery in a simulated South African population. This simulation suggests that pregnant women warrant specialized VL monitoring approaches different from non-pregnant adults, with considerations for gestational age.